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This version was published on July 1, 2008
Journal of Attention Disorders, Vol. 12, No. 1, 64-69 (2008)
DOI: 10.1177/1087054707305168

Injury Among Stimulant-Treated Youth With ADHD

Steven C. Marcus

University of Pennsylvania School of Social Policy & Practice

George J. Wan

Ortho-McNeil Janssen Scientific Affairs, LLC

Huabin F. Zhang

Ortho-McNeil Janssen Scientific Affairs, LLC

Mark Olfson

New York State Psychiatric Institute; Columbia University, mo49@.columbia.edu

Objective: To assess risk factors for injury among children and adolescents treated with stimulants for ADHD. Method: An analysis was performed of pharmacy and service claims data from 2000-2003 California Medicaid (Medi-Cal) focusing on children and adolescents ages 6 to 17 years who initiated stimulant therapy for ADHD. Bivariate and multivariate analyses were performed to examine associations of demographic and clinical characteristics with injury. Results: In a Cox proportional hazard model that controlled for background patient characteristics, patients ages 13 to 17 years, male gender, prescription of anxiolytic/hypnotic medications, and diagnosis of a mood disorder were each independently associated with increased risk of injury, whereas African American ancestry and other minority racial/ethnic ancestry were associated with lower risk. Youth with high stimulant medication possession ratios (MPR) had a nonsignificantly lower risk of injury as compared to those with a low stimulant MPR. Conclusion: These findings reveal several patient characteristics that may be associated with increased risk of injury among children and adolescents treated for ADHD. (J. of Att. Dis. 2008; 12(1) 64-69)

Key Words: stimulants • injury • ADHD


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